- 2000 - From the Corner of His Eye
- 2001 - One Door Away from Heaven
- 2001 - The Paper Doorway : Funny Verse and Nothing Worse, a children's book
- 2001 - "Qual Con", short fiction
- 2002 - By the Light of the Moon
- 2003 - The Face
- 2003 - Odd Thomas
- 2003 - Every Day's a Holiday : Amusing Rhymes for Happy Times, a children's book
- 2003 - The Book Of Counted Sorrows, poetry collection
- 2004 - The Taking
- 2004 - Life Expectancy
- 2004 - Robot Santa: The Further Adventures of Santa's Twin, a children's book
- 2004 - Life is Good! Lessons in Joyful Living (with Trixie Koontz), nonfiction
- 2005 - Prodigal Son (with Kevin J. Anderson), Book One in the Dean Koontz's Frankenstein series
- 2005 - Velocity
- 2005 - City of Night (with Ed Gorman), Book Two in the Dean Koontz's Frankenstein series
- 2005 - Forever Odd
- 2005 - Christmas Is Good!: Trixie Treats And Holiday Wisdom (with Trixie Koontz), nonfiction
- 2005 - Dean Koontz's Frankenstein, screenplay
- 2006 - The Husband
- 2006 - Brother Odd
- 2007 - The Good Guy
- 2007 - The Darkest Evening of the Year
- 2008 - Odd Hours
- 2008 - In Odd We Trust
- 2008 -Bliss to You: Trixie's Guide to a Happy Life with Trixie Koontz
- 2008 - Your Heart Belongs to Me

